Utrecht University

Biomedical Solid-State NMR

Utrecht University

Selected Recent Publications 

A. Shukla, R., Medeiros-Silva, J., Parmar, A., Vermeulen, B.J.A., Das, S.,  Paioni, L.A.,Jekhmane, S., Lorent, J., Bonvin, A.M.J.J., Baldus, M., Lelli, M., Veldhuizen, E., Breukink, E., Singh, I., Weingarth, M. (2020) Nature Communications, 11, 2848, Mode of action of teixobactins in cellular membranes See also press release

B. Jekhmane, S., Medeiros-Silva, J., Li, J., Kümmerer, F., Müller-Hermes, C., Baldus, M., Roux, B., Weingarth, M. (2019) Nature Communications, 10, 12 Shifts in the selectivity filter dynamics cause modal gating in K+ channels See also press release

C. Jekhmane, S., Prachar, M., J., Pugliese, R., Fontana, F., Medeiros-Silva, Gelain, F., Weingarth, M., (2019) Angewandte Chemie, 58, 16943, Design parameters of tissue engineering scaffolds at atomic scale

D. Medeiros-Silva, J., Jekhmane, S.,  Paioni, A., Gawarecka, K., Baldus, M., Swiezewska, E., Breukink, E., Weingarth, M. (2018) Nature Communications, 9, 3963, High-resolution NMR studies of antibiotics in cellular membranes  See also press release & coverage & coverage 



Publications 

  • 53.  Rohaim, A., Vermeulen, B., Li, J., Kümmerer, F., Napoli, F., Blachowicz, Medeiros-Silva, J., Roux., B., Weingarth, M., A different mechanism of C-type inactivation in the Kv-like KcsA mutant E71V, submitted
  • 52. Rončević1, T., Gerdol, M., Mardirossian, M., Maleš, M., Cvjetan, S., Benincasa, M., Maravić, A., Gajski, G., Krce, L., Aviani, I., Hrabar, J., Trumbić, J., Derks, M., Pallavicini, A., Weingarth, M., Zoranić, L., Tossi, A., Mladineo, I., Anisaxins, helical antimicrobial peptides from marine parasites, kill resistant bacteria by lipid extraction and membrane disruption, submitted
  • 51. Shukla, R., Lavore, F.,  Derks, M., Becker, L.M., Vermeulen, B., Wang, X., Kumar, R., Medeiros-Silva, J., Bonvin, AMJJ, Lorent, J., Lelli, M., Peoples, AJ., Spoering, AL., Ling, LL., Hughes, DE., Breukink, E., Lewis, K., Weingarth, M., Teixobactin kills bacteria by a two-pronged attack on the cell envelope, in revision
  • 50.  Zhao, X., Wang., X., Shukla, R., Kumar, R., Weingarth, M., Breukink, E., Kuipers, O., (2021), Frontiers Microbiology, Brevibacillin 2V exerts its bactericidal activity via binding to Lipid II and permeabilizing cellular membranes