Biomedical Solid-State NMR

Koen's new paper in Angewandte has been selected as a Frontispiece

Way to go!!

Koen Visscher, a former Master student in our group, has just published an article on ion channel clusters,

Supramolecular organization and functional implications of K+ channel clusters in membranes, which was accepted in Angewandte Chemie.

We used a novel approach that combines dynamic nuclear polarizaiton-enhanced solid-state NMR experiments and large-scale computer simulations. With this approach, we were able to show that potassium channel clustering depends on the gating state of the channels. Our study demonstrates a link between potassium channel clustering and function, and uncovers a hitherto unknown mechanism of ion channel communication. 

This approach can be used to study membrane protein - membrane protein interactions in a broad context.

Way to go Koen!

We welcome Barend Elenbaas, who will stay with us for six months for his Master Project.

We welcome Felix Torres, a Master student, in our group!

Felix will stay with us for six months.

We welcome Christoph Müller-Hermes in the group. Christoph will stay with us for three months.

Our article '1H-detected solid-state NMR studies of water-inaccessible proteins in vitro and in situ' has just been accepted.

Congrats João!