Our research focuses on the structure - activity analysis of membrane-active antibiotics. These antibiotics are often not only active against multi-drug resistant bacteria, they are also refractory against antimicrobial resistance development.
Understanding these antibiotics compellingly requires studies in a natural lipid environment, and ideally cell membranes. And yup - modern solid-state NMR spectroscopy is uniquely suited for this task! But hold on: we not only do solid-state NMR (that would be easy). We also extensively study antibiotic binding affinities, produce antibiotics in bacteria, etc.